6-Mercaptopurine, Purine antimetabolite and immunomodulator (TBI4698)
$45.00 – $72.00
Purine antimetabolite and immunomodulator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4698-200MG | Yes | 200mg | $45.00 | |||
TBI4698-1G | Yes | 1 G | $72.00 |
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Description
Product Details
Formal Name: 3,7-Dihydropurine-6-thione monohydrate
Alternate Names: 6-MP
Molecular Formula: C5H4N4S·H2O
Formula Weight: 170.19
CAS Number: 6112-76-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
Storage: RT
Stability: ≥ 2 years.
Applications
Purine antimetabolite and immunomodulator
Functions
Purine antimetabolite drug used to treat acute lymphocytic leukemia, Crohn’s disease, ulcerative colitis, and inflammatory bowel disease. It inhibits DNA synthesis by inhibiting the production of purine containing nucleotides. The immunomodulatory activity of 6-Mercaptopurine is mainly the result of the 6-MP metabolite 6-thioguanine triphosphate (6-TGTP) binding to small GTPase Rac1.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 200mg, 1 G |
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