5-Azacytidine, DNA hypomethylation agent (TBI1267)
$36.00 – $144.00
DNA hypomethylation agent
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1267-50MG | Yes | 50 MG | $36.00 | |||
TBI1267-250MG | Yes | 250 MG | $144.00 |
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Description
Product Details
Formal Name: 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Alternate Names: Ladakamycin; U-18496; NSC-102816; AzaC
Molecular Formula: C8H12N4O5
Formula Weight: 244.21
CAS Number: 320-67-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
DNA hypomethylation agent
Functions
Specific inhibitor of DNA methyltransferase. Incorporates into DNA and covalently reacts with and inhibits DNA methyltransferases. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Induces cardiac differentiation of human mesenchymal stem cells by activating ERK. Induces apoptosis in multiple myeloma cells via ATR-mediated DNA double strand breaks. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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