Articles

Tribio™ Tryptase Activity Assay

Tryptase, a tetrameric serine proteinase, has emerged as the major component of mast cell granules. Tryptase comprises up to 20% of the total protein of mast cells derived from lung, colon, and skin tissue. Because it is stored almost exclusively in mast cells, tryptase is a popular indicator of mast cell activation and a target for therapeutic intervention in allergic diseases. Related Products: β-Hexosaminidase Activity Assay (TBS2105)Cytochrome C Oxidase Activity Assay (TBS2115)Fast Glucose Determination Assay (TBS2087)

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Why Some People Are More Susceptible to SARS-CoV-2?

As COVID19 continues to rage across the US and around the world, scientists and physicians continue to be perplexed by why some younger patients with no underlying conditions succumb to SARS-CoV-2. In addition, these victims are disproportionately male. Now a research article published in Science by Bastard et al. may have provided some clues to the mystery. Bastard’s research shows that about 14% of critically ill COVID19 patients have autoantibodies against Type I interferons, namely IFN α2 and IFN ω. A...

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Monitor Cytokine Storms with Cutting-Edge Technology

COVID19 pandemic and CAR-T cell therapy have put Cytokine Release Syndrome (CRS), commonly known as cytokine storm, in the spotlight. Cytokine storms are caused by inflammation-causing cytokines released by activated T cells.  These cytokines include IFNg, TNFα, IL-1, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, IL-13, IL-17A, IL-22, GM-CSF, Granzyme B, and MIP-1α. Therefore, detections of these cytokines are paramount for monitoring cytokine storms. Traditional ELISA requires lengthy incubation periods at different temperatures and multiple wash steps. It is known to be...

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New Products

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