Norquetiapine 2HCl, Quetiapine metabolite; Norepiniphrine transport inhibitor (TBI2588)
$108.00 – $432.00
Quetiapine metabolite; Norepiniphrine transport inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2588-50MG | Yes | 50 MG | $108.00 | |||
TBI2588-250MG | Yes | 250 MG | $432.00 |
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Description
Product Details
Formal Name: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
Molecular Formula: C17H17N3S 2HCl
Formula Weight: 368.32
CAS Number: 111974-74-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO, methanol and water
Storage: RT
Stability: ≥ 1 year.
Applications
Quetiapine metabolite; Norepiniphrine transport inhibitor
Functions
Pharmacologically active metabolite of quetiapine. Exhibits distinct pharmacological activity from quetiapine and plays an important role in its antidepressant activity. Activates ERK1/2 and induces release of BDNF in C6 glioma cells which may contribute to the antidepressant properties of quetiapine. Inhibits the norepinephrine transporter which may contribute to the antipsychotic activity of quetiapine.
Application Procedures
First dissolved in DMSO, methanol and water, then diluted to aqueous buffer. Solutions in DMSO, methanol, or distilled water may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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