Doramapimod, p38 MAPK inhibitor (TBI2128)
$90.00 – $360.00
p38 MAPK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2128-5MG | Yes | 5 MG | $90.00 | |||
TBI2128-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: 1-[5-tert-Butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalene-1-yl]urea
Alternate Names: BIRB-796
Molecular Formula: C31H37N5O3
Formula Weight: 527.66
CAS Number: 285983-48-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
p38 MAPK inhibitor
Functions
Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site. (IC50=18 nM). Displays anti-inflammatory activity but differential effects on inflammatory genes. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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