Lorcainide HCl, Voltage-gated sodium channel blocker (TBI1157)
$90.00 – $270.00
Voltage-gated sodium channel blocker
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1157-5MG | Yes | 5 MG | $90.00 | |||
TBI1157-25MG | Yes | 25 MG | $270.00 |
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Description
Product Details
Formal Name: N-(4-Chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide hydrochloride
Molecular Formula: C22H27ClN2O • HCl
Formula Weight: 407.38
CAS Number: 58934-46-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Voltage-gated sodium channel blocker
Functions
Voltage-gated Na+ channel blocker. Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation. Acts at the ouabain binding site of guinea pig cardiac Na+/K+ ATPase and inhibits the enzyme (IC50 = 34 μM).
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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