Purmorphamine, Smoothened activator (TBI4622)
$135.00 – $450.00
Smoothened activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4622-5MG | Yes | 5 MG | $135.00 | |||
TBI4622-25MG | Yes | 25 MG | $450.00 |
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Description
Product Details
Formal Name: 1-(1-Napthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
Molecular Formula: C31H32N6O2
Formula Weight: 520.62
CAS Number: 483367-10-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Smoothened activator
Functions
Purmorphamine induces osteogenesis in multipotent mesenchymal progenitor cells via activation of hedgehog signaling. Activation of hedgehog is achieved via direct targeting of Smoothened. Purmorphamine has also been used as part of a “cocktail” of small molecules to reprogram mouse somatic cells into pluripotent stem-like cells and human Astroglial cells into functional neurons.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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