N-Acetyl-S-farnesyl-L-cysteine, S-Farnesylcyteine methyl transferase inhibitor (TBI4610)
$90.00 – $351.00
S-Farnesylcyteine methyl transferase inhibitor
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBI4610-5MG | Yes | 5 MG | $90.00 | |||
| TBI4610-25MG | Yes | 25 MG | $351.00 |
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Description
Product Details
Formal Name: 2-Acetamido-3-(3,7,11-trimethyldodeca-2,6,10-trienylsulfanyl)propanoic acid
Alternate Names: AFC
Molecular Formula: C20H33NO3S
Formula Weight: 367.60
CAS Number: 135304-07-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 25 mg/ml) or Ethanol (up to at least 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
S-Farnesylcyteine methyl transferase inhibitor
Functions
N-Acetyl-S-farnesyl-L-cysteine (AFC) inhibits S-farnesylcysteine methyl transferase (Km = 20 µM). AFC blocked capacitative Ca2+ influx in human embryonic kidney 293 cells and store-regulated Ca2+ entry in human platelets. Topical AFC has been shown to inhibit neutrophil chemotaxis and other inflammatory responses without systemic effects.
Application Procedures
First dissolved in DMSO (up to at least 25 mg/ml) or Ethanol (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
| SIZE (mg) | 25 MG, 5 MG |
|---|
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