BD1063 dihydrochloride, Selective sigma-1 antagonist (TBI4211)
$90.00 – $351.00
Selective sigma-1 antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4211-5MG | Yes | 5 MG | $90.00 | |||
TBI4211-25MG | Yes | 25 MG | $351.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride
Molecular Formula: C13H18Cl2N2·2HCl
Formula Weight: 346.13
CAS Number: 206996-13-6
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (up to at least 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Selective sigma-1 antagonist
Functions
BD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM). BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner. BD1063 potentiated µ-opioid antinociception in mice in a sigma-dependent manner. BD-1063 has been used in animal models to successfully treat compulsive eating and excessive ethanol drinking.
Application Procedures
First dissolved in Water (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “BD1063 dihydrochloride, Selective sigma-1 antagonist (TBI4211)”
You must be logged in to post a review.
Reviews
There are no reviews yet.