ICA-110381, Potassium Kv7.2/7.3 channel activator (TBI1467)

$90.00$270.00

Potassium Kv7.2/7.3 channel activator

SKU: TBI1467 Category:
SKUStock SIZE (mg) PriceQuantity
TBI1467-5MG Yes 5 MG $90.00
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TBI1467-25MG Yes 25 MG $270.00
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Description

Product Details

Formal Name: 4-Chloro-N-(6-chloro-3-pyridinyl)benzamide

Molecular Formula: C12H8Cl2N2O

Formula Weight: 267.12

CAS Number: 325457-99-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 26 mg/ml) or in Ethanol (up to 5 mg/ml).

Storage: RT

Stability: ≥ 2 years.

 

Applications

Potassium Kv7.2/7.3 channel activator

 

Functions

A KCNQ2/Q3 (Kv7.2/7.3) activator, EC50=0.38 μM (KCNQ1 IC50=15 μM). KCNQ3/Q5 heterodimers are not affected. Potently dampens neuronal excitability and displays anticonvulsant activity in vivo.

 

Application Procedures

First dissolved in DMSO (up to 26 mg/ml) or in Ethanol (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Additional information

SIZE (mg)

25 MG, 5 MG

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