AG-879, NGFR kinase inhibitor (TBI1090)
$126.00 – $504.00
NGFR kinase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1090-5MG | Yes | 5 MG | $126.00 | |||
TBI1090-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: 3,5-Di-t-butyl-4-hydroxybenzylidene cyanothioacetamide
Molecular Formula: C18H24N2OS
Formula Weight: 316.47
CAS Number: 148741-30-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
NGFR kinase inhibitor
Functions
Inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 µM). No inhibition of EGF, or PDGF receptor phosphorylation at typical working concentrations.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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