iGP-1, Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor (TBI3881)
$90.00 – $324.00
Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3881-5MG | Yes | 5 MG | $90.00 | |||
TBI3881-25MG | Yes | 25 MG | $324.00 |
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Description
Product Details
Formal Name: N-[4-(1H-Benzoimidazol-2-yl)-phenyl]-succinamic acid
Molecular Formula: C17H15N3O3
Formula Weight: 309.30
CAS Number: 27031-00-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO up to 50 mg/ml
Storage: -20°C
Stability: ≥ 1 year.
Applications
Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor
Functions
A potent and cell permeable inhibitor of the mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 μM, which is selective over the cytosolic enzyme. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.
Application Procedures
First dissolved in DMSO up to 50 mg/ml, then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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