Vinblastine sulfate, Microtubule depolymerizer (TBI2050)

$86.00$346.00

Microtubule depolymerizer

SKU: TBI2050 Category:
SKUStock SIZE (mg) PriceQuantity
TBI2050-5MG Yes 5 MG $86.00
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TBI2050-25MG Yes 25 MG $346.00
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Description

Product Details

Alternate Names: Vincaleukoblastine

Molecular Formula: C46H58N4O9 · H2SO4

Formula Weight: 909.08

CAS Number: 143-67-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Water (up to 50 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

Microtubule depolymerizer

 

Functions

Semisynthetic alkaloidal anticancer agent. Induces cell cycle arrest at G2/M phase by inhibiting mitotic spindle formation. Inhibits normal microtubule assembly and induces aberant tubulin polymerization1. Induces apoptosis in a variety of cell lines. Inhibits autophagosome maturation. Inhibits palmitoylation of tubulin.

 

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Water (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.

Additional information

SIZE (mg)

25 MG, 5 MG

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