WHI-P131, JAK3 inhibitor (TBI1190)
$108.00 – $432.00
JAK3 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1190-5MG | Yes | 5 MG | $108.00 | |||
TBI1190-25MG | Yes | 25 MG | $432.00 |
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Description
Product Details
Formal Name: 4-[(4’-hydroxyphenyl)amino]-6,7-dimehtoxyquinazoline
Alternate Names: JANEX-1
Molecular Formula: C16H15N3O3 · HCl
Formula Weight: 333.78
CAS Number: 202475-60-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
JAK3 inhibitor
Functions
JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion. Increases survival in a mouse ALS model. Delays or prevents autoimmune type 1 diabetes in NOD mice. Exhibits potent anti-inflammatory activity in mouse models of peritonitis, colitis, cellulitis and systemic inflammatory response syndrome. Displays protective effects against myocardial ischemia and reperfusion injury in mouse models.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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