H2L5186303, LPA2 antagonist (TBI1452)

Description

Product Details

Formal Name: (Z,Z)-4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid]

Molecular Formula: C₂₆H₂₀N₂O₈

Formula Weight: 488.45

CAS Number: 139262-76-3

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

LPA2 antagonist

 

Functions

Potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist.  IC50 = 8.9 nM, 1230 nM and 27.35 µM for LPA2, LPA3, and LPA1 respectively.

 

Application Procedures

First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.

Additional information

SIZE (mg)	25 MG, 5 MG

Datasheet:

TBI1452_H2L5186303

MSDS:

TBI1452_H2L5186303_MSDS_2024