Tofacitinib, JAK inhibitor (TBI2177)
$108.00 – $396.00
JAK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2177-5MG | Yes | 5 MG | $108.00 | |||
TBI2177-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidine-propanenitrile
Alternate Names: Tasocitinib; CP-690550
Molecular Formula: C16H20N6O
Formula Weight: 312.40
CAS Number: 477600-75-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
JAK inhibitor
Functions
Potent pan-JAK inhibitor, IC50s=1, 20 and 112 nM for JAK3, JAK2 and JAK1 respectively. Displays potent antiinflammatory and immunosuppressant activity. Promotes a white-to-brown metabolic conversion in human adipocytes. In therapeutic use for rheumatoid arthritis.
Application Procedures
First dissolved in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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