Guggulsterone (Z-), FXR antagonist (TBI3816)
$137.00 – $540.00
FXR antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3816-5MG | Yes | 5 MG | $137.00 | |||
TBI3816-25MG | Yes | 25 MG | $540.00 |
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Description
Product Details
Formal Name: (Z)-Pregna-4,17(20)-diene-3,16-dione
Molecular Formula: C21H28O2
Formula Weight: 312.45
CAS Number: 39025-23-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 6 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming)
Storage: -20°C
Stability: ≥ 2 years.
Applications
FXR antagonist
Functions
A natural steroid from Commiphora mukul extract (guggulipid) which lowers cholesterol and acts as an FXR antagonist. Attenuates astrocyte-mediated neuroinflam-mation. Induces differentiation of pluripotent stem cells to dopaminergic neurons. Produces antidepressant-like effects via activation of the BDNF signaling pathway in mouse models.
Application Procedures
First dissolved in DMSO (up to 6 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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