Ascomycin, FKBP ligand; immunosupressant (TBI2059)
$63.00 – $216.00
FKBP ligand; immunosupressant
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2059-5MG | Yes | 5 MG | $63.00 | |||
TBI2059-25MG | Yes | 25 MG | $216.00 |
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Description
Product Details
Formal Name: Fermentation product from Streptomyces hygroscopicus
Alternate Names: FK-520; FR-900520
Molecular Formula: C43H69NO12
Formula Weight: 729.03
CAS Number: 104987-12-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
FKBP ligand; immunosupressant
Functions
Analog of FK-506. Potent immunosuppressant. Binds to FKBP12 and inhibits calcineurin and NFAT. Displays antiinflammatory effects in skin diseases. Cell permeable and active in vivo.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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