Veratramine, Cyclopamine analog (TBI1147)

Description

Product Details

Formal Name: (3β, 23β)-14,15,16,17-Tetrahydroveratraman-3,23-diol

Alternate Names: NSC 17821; NSC 23880

Molecular Formula: C₂₇H₃₉NO₂

Formula Weight: 409.60

CAS Number: 60-70-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 12 mg/ml) or in Ethanol (up to 10 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

 

Applications

Cyclopamine analog

 

Functions

Veratramine is a teratogenic steroidal alkaloid found in the corn lily (Veratrum sp.). It is an analog of cyclopamine which can inhibit the hedgehog signaling pathway-dependent proliferation in NIH/3T3 cells at 8 μM.  Cell permeable. SPECIAL HANDLING PRECAUTIONS: This product is teratogenic. Women who are, or may be pregnant should not handle this compound.

 

Application Procedures

First dissolved in DMSO (up to 12 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Additional information

SIZE (mg)	25 MG, 5 MG

TBI1147_Data_Sheet