Bedaquiline, Antituberculosis/SARS-CoV2 3CLpro inhibitor (TBI4403)
$90.00 – $297.00
Antituberculosis/SARS-CoV2 3CLpro inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4403-5MG | Yes | 5 MG | $90.00 | |||
TBI4403-25MG | Yes | 25 MG | $297.00 |
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Description
Product Details
Formal Name: (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol
Alternate Names: TMC207; R207910
Molecular Formula: C32H31BrN2O2
Formula Weight: 555.50
CAS Number: 843663-66-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml)
Storage: RT
Stability: ≥ 1 year.
Applications
Antituberculosis/SARS-CoV2 3CLpro inhibitor
Functions
Clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains. It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE) and subunit ε of ATP synthase inhibiting ATP production. Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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