SB-431542, ALK4,5 and 7 inhibitor (TBI2443)
$126.00 – $396.00
ALK4,5 and 7 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2443-5MG | Yes | 5 MG | $126.00 | |||
TBI2443-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Molecular Formula: C22H16N4O3
Formula Weight: 384.40
CAS Number: 301836-41-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 3 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
ALK4,5 and 7 inhibitor
Functions
Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM). Inhibits TGFβ-induced proliferation of human osteosarcoma cells. Ehances growth and integrity of embryonic stem cell-derived endothelial cells. A frequently used agent employed in numerous stem cell differentiation protocols. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml), or in Ethanol (up to 3 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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