Hypothemycin, MEK inhibitor (TBI2483)
$108.00 – $360.00
MEK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2483-200UG | Yes | 200 µg | $108.00 | |||
TBI2483-1MG | Yes | 1 MG | $360.00 |
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Description
Product Details
Formal Name: Natural product isolated from Phoma sp.
Molecular Formula: C19H22O8
Formula Weight: 378.37
CAS Number: 76958-67-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
MEK inhibitor
Functions
Potent and selective inhibitor of MEK. Acts via covalent binding to Cys residue. In cells, hypothemycin inhibits the MEK-ERK axis with sufficient selectivity to normalize transformed phenotypes. Inhibits TNFα production in LPS-stimulated macrophages.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 1 MG, 200 µg |
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