Microcystin LR, Protein phosphatase PP1 and PP2A inhibitor (TBI2719)
$108.00 – $432.00
Protein phosphatase PP1 and PP2A inhibitor
SKU | Stock | SIZE | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2719-100UG | Yes | 100 µg | $108.00 | |||
TBI2719-500UG | Yes | 500 µg | $432.00 |
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Description
Product Details
Formal Name: Isolated from Microcystis aeruginosa (a freshwater cyanobacteria)
Molecular Formula: C49H74N10O12
Formula Weight: 995.17
CAS Number: 101043-37-2
Purity: >95%
Formulation: powder
Solubility: Soluble in DMSO, methanol, and ethanol
Storage: -20°C
Stability: ≥ 1 year.
Applications
Protein phosphatase PP1 and PP2A inhibitor
Functions
A novel freshwater cyanotoxin. Tumor promoter. Potent and selective inhibitor of protein phosphatase 2A (PP2A), IC50=0.04 nM. PP1, IC50=1.7 nM and PP2B are less sensitive and PP2C is not inhibited (up to 4 μM). Considered to be cell-impermeable with the exception of hepatocytes which take it up via an organic anion transporter.
Application Procedures
First dissolved in DMSO, methanol, and ethanol, then diluted to aqueous buffer. Solutions in DMSO, methanol, and ethanol may be stored at -20°C for up to 2 months.
Additional information
SIZE | 100 µg, 500 µg |
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