Bongkrekic acid, Mitochondrial permeability pore inhibitor (TBI2751)

$288.00$900.00

Mitochondrial permeability pore inhibitor

SKU: TBI2751 Category:
SKUStock SIZE PriceQuantity
TBI2751-100UG Yes 100 µg $288.00
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TBI2751-500UG Yes 500 µg $900.00
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Description

Product Details

Formal Name: 3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid

Molecular Formula: C28H38O7 (free acid)

Formula Weight: 486.60

CAS Number: 11076-19-0

Purity: >98%

Formulation: Solution of 1mg/ml in Tris buffer

Solubility: Miscible with DMSO

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

Mitochondrial permeability pore inhibitor

 

Functions

A potent inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT). Inhibits mitochondrial permeability transition pore opening. Delivery of bongkrekic acid to the mitochondria prevents apoptosis in HeLa cells.

 

Application Procedures

First dissolved in DMSO, then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.

Additional information

SIZE

100 µg, 500 µg

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