Thalidomide, E3 Ubiquitin ligase inhibitor (TBI1115)
$90.00 – $360.00
E3 Ubiquitin ligase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1115-100MG | Yes | 100 MG | $90.00 | |||
TBI1115-500MG | Yes | 500 MG | $360.00 |
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Description
Product Details
Formal Name: N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemic
Molecular Formula: C13H10N2O4
Formula Weight: 326.82
CAS Number: 50-35-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 5 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
E3 Ubiquitin ligase inhibitor
Functions
Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 500 MG, 100 MG |
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