Epoxomicin, Irreversible 20S proteasome inhibitor (TBI1384)
$279.00
Irreversible 20S proteasome inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1384-100UG | Yes | 100 UG | $279.00 |
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Description
Product Details
Molecular Formula: C28H50N4O7
Formula Weight: 554.73
CAS Number: 134381-21-8
Purity: >98%
Formulation: Lyophilized
Solubility: Soluble in DMSO (up to 10 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Irreversible 20S proteasome inhibitor
Functions
Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome. It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 µM. Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells. Epoxomicin caused a progressive model of Parkinson’s disease in various systems. This model has been disputed.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
 
Additional information
SIZE (mg) | 100 UG |
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