NSC-66811 p53/mdm2 inhibitor (TBI1334)
$180.00 – $720.00
p53/mdm2 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1334-10MG | Yes | 10 MG | $180.00 | |||
TBI1334-50MG | Yes | 50 MG | $720.00 |
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Description
Product Details
Formal Name: 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol
Molecular Formula: C23H20N2O
Formula Weight: 340.43
CAS Number: 6964-62-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
p53/mdm2 inhibitor
Functions
A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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