Decylubiquinone, MPTP inhibitor (TBI2580)

Description

Product Details

Formal Name: 2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone

Molecular Formula: C₁₉H₃₀O₄

Formula Weight: 322.44

CAS Number: 55486-00-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 10 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

MPTP inhibitor

 

Functions

Inhibits the Ca2+ dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration. Maximum effect on Ca2+ retention capacity of rat liver mitochondria at 100 μM. Inhibits etoposide-induced apoptosis in L929 cells at 5 μM via inhibition of cytochrome c release. Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function. Substrate for various quinone oxidoreductases.

 

Application Procedures

First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.

 

Additional information

SIZE (mg)	10 MG, 50 MG

Datasheet:

TBI2580_Decylubiquinone