Lapatinib (base), EGFR and HER2 inhibitor (TBI2147)
$99.00 – $234.00
EGFR and HER2 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2147-10MG | Yes | 10 MG | $99.00 | |||
TBI2147-50MG | Yes | 50 MG | $234.00 |
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Description
Product Details
Formal Name: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine
Alternate Names: GW-572016
Molecular Formula: C29H26ClFN4O4S
Formula Weight: 581.06
CAS Number: 231277-92-2
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 200 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
EGFR and HER2 inhibitor
Functions
Potent inhibitor of EGFR kinase (Ki=3 nM), Erb-2 kinase (Ki=13 nM) Erb-4 kinase (Ki=347 nM). Clinically useful agent for treatment of breast cancer. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 200 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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