Entacapone, COMT inhibitor; Anti-Parkinsons (TBI2025)
$72.00 – $198.00
COMT inhibitor; Anti-Parkinsons
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2025-10MG | Yes | 10 MG | $72.00 | |||
TBI2025-50MG | Yes | 50 MG | $198.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
Molecular Formula: C14H15N3O5
Formula Weight: 305.29
CAS Number: 130929-57-6
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 3 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
COMT inhibitor; Anti-Parkinsons
Functions
Potent catechol O-methyltransferase (COMT) inhibitor (IC50 = 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of L-DOPA as adjunct therapy for Parkinson’s disease. Inhibits α-synuclein aggregation in vitro and inhibits α-synuclein-induced cell death in PC-12 cells. Antioxidant. Inhibits oxidative stress-induced cell death.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 3 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 10 MG, 50 MG |
---|
Be the first to review “Entacapone, COMT inhibitor; Anti-Parkinsons (TBI2025)”
You must be logged in to post a review.
Reviews
There are no reviews yet.