Ribociclib, CDK4/6 inhibitor (TBI4807)
$126.00 – $405.00
CDK4/6 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4807-10MG | Yes | 10 MG | $126.00 | |||
TBI4807-50MG | Yes | 50 MG | $405.00 |
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Description
Product Details
Formal Name: 7-Cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Alternate Names: LEE011
Molecular Formula: C23H30N8O3
Formula Weight: 434.5
CAS Number: 1211441-98-3
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
CDK4/6 inhibitor
Functions
Potent and selective CDK 4/6 inhibitor1. Mitigates acute kidney injury. Induces cell cycle arrest and senescence in neuroblastoma. In clinical use for HR-positive, HER2-negative metastatic breast cancer. Orally bioavailable.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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