Services

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Northern Blot Service

Northern blot is a molecular biological technique first developed in 1977, known for its wide application on gene expression, disease diagnosis, and viral microRNAs detection, etc. It is a classical methodology to characterize and quantitate specific RNA genes in the sample matrix. The northern analysis first starts from RNA extraction from tissues or cells, which are further separated by denaturing agarose gels. The separated RNAs are transferred to a nylon membrane with capillary forces. RNA on the membrane is then hybridized with complementary probes for detection, which could be labeled with biotin, Digoxigenin conjugated or radioactive isotope-labeled (Figure 1 as below). With increasingly strict regulatory requirements on radiation exposure, Tribioscience has specialized in non-radioactive Northern blot technical development to meet urgent scientific needs. Our team expertise is dedicated to providing high-quality and timely service to meet our customers’ expectations.

Figure 1.

Tribioscience aims to save customers time and effort by providing one-stop service:

RNA purification and integration analysis
RNA gel separation with greener denaturing system
RNA membrane transfer
Sensitive probe labeling
Probe hybridization
Image development and data analysis

Contact us:

Phone: 408-498-0197

Email: [email protected]

Address: 365 San Aleso Ave., Sunnyvale, CA 94085

  • RNA isolation and purification
  • Genomic DNA isolation and purification
  • Plasmid DNA isolation and purification
  • RT- PCR system
  • Gene Cloning
  • Viral vectors

  • Biochemical assays including enzyme activity
  • Immunoassays including antibodies, ELISA, and lateral flow test
  • Cell-based assays

Pain models including postsurgical pain, inflammatory pain, joint pain, fracture injury pain, traumatic brain injury pain, neuropathic pain, and drug addict models.

Animal Model services

Neuromodel division of Tribioscience specializes in preclinical in-vivo model services for potential therapeutics relevant to neurological disorders. The company provides high-quality, timely and confidential consulting services with a variety of inflammatory, pain and neurodegeneration animal models, dosing route and relative assays.

Pain models

Arthritis joint pain, osteoarthritis joint pain, formalin test, complete freund’s adjuvant (CFA), plantar incision, neuropathic pain, acute pain and compound

Brain disorder models

Trauma brain injury (TBI) models, spinal cord injury, stroke

Drug delivery routes

Intravenous (i.v.) injection and continuous vein infiltration, intrathecal (i.t.) injection, intraarticular (i.a.) injection and brain stereotaxic injection.

Behavioral test models

Thermal hyperalgesia, mechanical allodynia and hyperalgesia, spontaneous pain response, weight bearing, gait analysis, local motor activity, rotarod test and grip force.

Infectious Disease Models
Click here for more information.

Fibrosis Models
Click here for more information.

Immune Disease Models
Click here for more information.

Cryptosporidium spp. Mouse Model
Click here for more information.



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Contact us by a call or an email to get a quote of your desiring products immediately.

Tel: 408-498-0197

Fax:650-618-5498

Email: [email protected]